Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants
This cohort study compares the cancer spectrum and frequencies between male BRCA1 and BRCA2 pathogenic variant carriers.
View ArticleShould All Patients With Pancreatic Cancer Receive Chemotherapy Before Surgery?
During the last decade, moderate progress in the treatment of pancreatic ductal adenocarcinoma (PDAC) has been realized with updated chemotherapeutic regimens, advanced operative techniques, and in...
View ArticleFirst-line FOLFIRINOX vs Gemcitabine and nab-Paclitaxel Treatment of...
This case series evaluates survival and radiographic and serologic measures of responses associated with administration of FOLFIRINOX or gemcitabine plus nab-paclitaxel as first-line chemotherapy in...
View ArticleA Man With Widespread Arthritis and Ill-Defined Cutaneous Lesions
A man in his 30s presented with a 3-month history of fourth finger right hand articular heat, pain, redness, and swelling, which developed into widespread arthritis accompanied by ill-defined skin...
View ArticleNeoadjuvant Treatment for Patients With Localized Pancreatic Adenocarcinoma
This Viewpoint advocates for increased use of neoadjuvant therapy in the treatment of localized pancreatic adenocarcinoma.
View ArticleCancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants
This cohort study compares the cancer spectrum and frequencies between male BRCA1 and BRCA2 pathogenic variant carriers.
View ArticleDiabetes, Weight Change, and Pancreatic Cancer Risk
This cohort study examines multiyear self-reported demographic, lifestyle choice, and medical history data to track weight changes, disease diagnoses, health outcomes, and other factors associated with...
View ArticleNICE Guidelines on the Diagnosis and Management of Pancreatic Cancer
This article summarizes “Diagnosis and Management of Pancreatic Cancer in Adults: A Summary of Guidelines From the UK National Institute for Health and Care Excellence,” which is aimed at improving...
View ArticleAdjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After...
This cohort study uses data from an existing cohort of patients undergoing resection of pancreatic cancer to assess the overall survival of patients treated with neoadjuvant FOLFIRINOX after surgery...
View ArticleA Man With Widespread Arthritis and Ill-Defined Cutaneous Lesions
A man in his 30s presented with a 3-month history of fourth finger right hand articular heat, pain, redness, and swelling, which developed into widespread arthritis accompanied by ill-defined skin...
View ArticleDiabetes, Weight Change, and Pancreatic Cancer Risk
This cohort study examines multiyear self-reported demographic, lifestyle choice, and medical history data to track weight changes, disease diagnoses, health outcomes, and other factors associated with...
View ArticleEvaluation of Outcomes Following Surgery for Locally Advanced Pancreatic...
This case series examines data from 2003 to 2018 regarding patients who underwent aggressive resection operative treatment for locally advanced pancreatic neuroendocrine tumors and their outcomes in...
View ArticleLooking to Long-term Survivors for Improved Pancreatic Cancer Treatment
This Medical News article examines how studying the characteristics of long-term pancreatic cancer survivors might improve treatment and boost survival for others who have the disease
View ArticleAssessing Risk for Low-Risk Branch-Duct Intraductal Papillary Mucinous Neoplasms
Gastroenterology and Hepatology
View ArticleFactors Associated With Progression of Branch-Duct Intraductal Papillary...
This cohort study examines the use of patient- and cyst-related factors available at baseline for estimation of the risk of progression in patients with branch-duct intraductal papillary mucinous...
View ArticleEfficacy of Perioperative Chemotherapy for Resectable Pancreatic Adenocarcinoma
This randomized clinical trial assesses the feasibility and clinical utility of neoadjuvant and adjuvant (perioperative) chemotherapy for treatment of patients with resectable pancreatic cancer.
View ArticleIntraoperative Neck Margin Assessment Reappraisal in Pancreaticoduodenectomy...
This narrative review summarizes research on the association of margin-negative resection of localized pancreatic ductal adenocarcinoma in patients with a microscopically positive intraoperative neck...
View ArticleAnti–PD-1 Immunotherapy in Microsatellite-Stable Tumors With 10 or More...
This cohort study examines the performance of a universal definition of high tumor mutational burden in an independent cohort of patients with solid tumors treated with immune checkpoint inhibitors.
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